What Is Nephrogenic Fibrosing Dermopathy/Nephrogenic Systemic Fibrosis?



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Nephrogenic Systemic Fibrosis

What Is Nephrogenic Fibrosing Dermopathy/Nephrogenic Systemic Fibrosis?
Nephrogenic Fibrosing Dermopathy NFD is an acquired disorder found in patients with renal failure. The disorder is also known as Nephrogenic Systemic Fibrosis NSF. This disorder causes fibrotic nodules and plaques to develop on the skin. Nephrogenic Fibrosing Dermopathy or Nephrogenic Systemic Fibrosis can also lead to limited range of motion, due to tightening of the skin and impaired joints.

For an extended period of time, the medical or biological cause of NFD/NSF was unknown.  The there was speculation that antiphospholipid or anticardiolipin antibodies were possible culprits. It was thought that they might react to a substance in the dialysis procedure.

The cause of this condition and/or disorder has now been linked to Gadolinium- a contrasting agent that is still used in MRI studies of patients. If you have symptoms of NSF or have been diagnosed with NSF or NFD and you have undergone an MRI with the contract agent of Gadolinium - call us toll free at 1-800-862-1260.